Hence ophthalmologists as doctors not only have much to offer to advance our own discipline but also to advance medicine as a whole. How does age affect the outcome of kidney transplantation in elderly recipients? It is clear from the literature that additional research is necessary to determine which factors are most closely related to renal transplantation outcomes and there are still several problems to be addressed. doi: 10.1016/j.jamcollsurg.2009.12.032, 12. When there are HLA mismatches, requirement for higher immunosuppression doses and more antirejection therapy are needed, thus it is associated with short-term adverse function because of infection or cardiovascular disease during the first year after kidney transplantation, which persisted but was far less marked during years 2–5 (35). Data extracted from the database for this analysis include: (1) Recipient-related factors: gender, age, BMI (calculated by height and weight), blood type, ethnicity, number of transplants, preoperative hepatitis history, type and duration of dialysis, and HLA A-B-DR-DQ loci mismatch; and (2) Donor-related factors: gender, age, blood type, and relationship to recipient. JZhu, WP, and TS provided expert advice and assisted data collecting. New advances in medicine and affiliated fields greatly impact the work of clinicians and call for interdisciplinary collaborations, emphasizing the need to remodel preparation programs for graduates in academic nephrology and clinical practice. Risk factors for acute rejection after deceased donor kidney transplantation in China. It was established in 2007 as Frontiers of Medicine in China, obtaining its current name in 2011. Clin J Am Soc Nephrol. The aim is to act as a platform for translational research between scientists and clinicians. In addition, the age of donors correlated with medium-and-long-term impact on kidney function. While the recipient who received a kidney from an older donor was a risk factor for CysC recovery from 2 weeks to 2 years (P < 0.05, OR > 1), as well as the recipients with large BMI from 2 weeks to 1 month (P < 0.05, OR > 1). Creatinine-based equations for estimation of GFR (eGFR) were established to overcome some of these inadequacies (40). Written informed consent from the participants' legal guardian/next of kin was not required to participate in this study in accordance with the national legislation and the institutional requirements. Interestingly, a recent publication by Cohen et al. However, due to increasing organ shortage during the last three decades, ABO incompatibility kidney transplantation has become a routine procedure and death-censored graft survival rates are comparable to those in compatible transplantation (13, 14). doi: 10.3760/cma.j.issn.0376-2491.2017.02.002, 20. ABO-incompatible kidney transplantation. Transplantation kidney function recovery in non-Han vs. Han Chinese individuals has not previously been investigated in China, but our results show that non-Han recipients have a better graft condition after kidney transplantation than Han recipients. FRONTIERS IN MEDICINE 2017. Heart Fail Rev. Further, the CysC value reflects the estimated glomerular filtration rate (eGFR) and thus shows the kidney condition of postoperative patients. However, this marker has several well-known limitations such as dependent on a number of factors including tubular resorption, total muscle mass, nutritional status, age and gender. Cippà PE, Schiesser M, Ekberg H, van Gelder T, Mueller NJ, Cao CA, et al. The Innovators in Science Award was established in 2016 as … Figure 3. doi: 10.1111/ctr.12191, 6. Kidney transplantation from donation after cardiac death donors: lack of impact of delayed graft function on post-transplant outcomes. This retrospective study was approved by the Biomedical Ethics Subcommittee of West China Hospital of Sichuan University [reference No. Transplantation. Frontiers Editorial Office Avenue du Tribunal Fédéral 34 CH – 1005 Lausanne Switzerland Tel +41(0)21 510 17 40 Fax +41 (0)21 510 17 01, medicine.editorial.office@frontiersin.org, Frontiers Support Tel +41(0)21 510 17 10 Fax +41 (0)21 510 17 01 support@frontiersin.org, Avenue du Tribunal Fédéral 34 CH – 1005 Lausanne Switzerland, Tel +41(0)21 510 17 40 Fax +41 (0)21 510 17 01, For all queries regarding manuscripts in Review and potential conflicts of interest, please contact Scope. 2015(288)]. Ophthalmology is one of the fastest advancing disciplines in medicine. J Clin Invest. Clin Transplant. Merion RM, Goodrich NP, Johnson RJ, McDonald SP, Russ GR, Gillespie BW, et al. There was a statistically significant difference in CysC recovery between female and male recipients from 1 day to 5 years after kidney transplantation (P < 0.001), with a faster recovery rate in female recipients. Chronic kidney disease (CKD) is a great global health burden due to its high associated risk of end-stage renal disease (ESRD) (1) and ESRD has been reported to affect an estimated 7.4 million people worldwide (2). (2012) 17:251–61. Using standardized serum creatinine values in the modification of diet in renal disease study equation for estimating glomerular filtration rate. Donor and recipient characteristics were enrolled and matched in the Transplant Center Database before transplantation. doi: 10.1016/j.transproceed.2012.08.014, 18. Note that 2019 Journal Impact are reported in 2020; they cannot be calculated until all of the 2019 publications have been processed by the indexing agency. (2002) 15:10–6. doi: 10.1111/ajt.14631, 10. Interestingly, in univariate analysis, we found no significant effect for matching blood group between donor and recipient, which was not consistent with clinical practice and previous knowledge. Frontiers in Cell and Developmental Biology. Multi-center data analysis would be an optimal next step to confirm the results. Nephrol Dial Transplant. BMC Health Serv Res. It has also been reported that live-donor transplantation after desensitization provided a significant survival benefit for patients with HLA sensitization, as compared to waiting for a compatible organ (34). According to the conditions of follow-up, the postoperative analysis time points were stratified as 1 day, 1, 2 weeks, 1, 3, 6 months, 1, 2, 3, 4, 5 years, and more than 5 years up to 10 years. (2009) 87:1246–55. CysC, a cysteine protease inhibitor, possesses many attributes required for the ideal eGFR marker. Recipients with HLA A-B-DR-DQ mismatches less than or equal to 4 accounted for the majority (73.2%). There are, however, some limitations in our study. Sex hormones and gender-related differences: their influence on chronic renal allograft rejection. Clin Transplant. BMC Nephrol. Journal Impact Prediction System provides an open, transparent, and straightforward platform to help academic researchers Predict future Metric and performance through the wisdom of crowds. doi: 10.1111/ajt.14694, 26. Therefore, we utilized CysC as postoperative outcome indicator rather than the traditional kidney biopsy and traditional laboratory indicators. Pesquisa Popular. (2018) 16:682–9. Frontiers in Medicine IF is decreased by a factor of 0.4 and approximate percentage change is -11.76% when compared to preceding year 2017, which shows a falling trend. Compatible ABO blood type was preferred, but when the matching was unsuccessful, the incompatible ABO kidney transplant was considered for reducing waiting time when kidney donors were extremely lacking. However, estimation equations are reliable only in stable conditions and should not be used when rapid changes of renal function occur (41). However, some studies have reported an additional 10–20% of living donor procedures were conducted by using ABO incompatible kidney transplantation (37, 38). Baskin-Bey ES, Kremers W, Nyberg SL. doi: 10.1093/ndt/gfu375, 37. Mills KT, Xu Y, Zhang W, Bundy JD, Chen CS, Kelly TN, et al. The goal of this study is to acquire information about inferior outcomes earlier to allow clinicians to make appropriate adjustments in therapy at specific time points, thereby enhancing the quality of life of patients. JCR was earlier published as Science Citation Index, and now it is published by Clarivate Analytics, a Web of Science Group. CKD, chronic kidney disease; ESRD, end-stage renal disease; CysC, cystatin C; DCD, donor after cardiac death; eGFR, estimated glomerular filtration rate; Cr, creatinine; BMI, body mass index. Takeda Pharmaceutical Company Limited . Transplantation. Based on these results, it is possible to expand the living donor pool for patients which may reduce waiting time and minimize suffering before transplantation. Inferior long-term allograft and patient outcomes among recipients of offspring living donor kidneys. doi: 10.1111/ctr.13036, 33. Africa . (2017) 8:234. doi: 10.3389/fimmu.2017.00234, 14. Frontiers in Medicine - Journal Impact The Journal Impact 2019-2020 of Frontiers in Medicine is 3.000, which is just updated in 2020. Williams A, Richardson C, McCready J, Anderson B, Khalil K, Tahir S, et al. In addition to the 2-year Journal Impact, the 3-year Journal Impact can provide further insights and factors into the impact of Frontiers in Neurology. Frontiers in Laboratory Medicine publishes rigorously peer-reviewed, high-quality original articles and authoritative reviews that focus on developments and advances in laboratory medicine. To our knowledge, West China Hospital of Sichuan University has done the largest number of kidney transplants in our country, and we retrospectively analyzed data from cases during the past decade. Donor-recipient gender and size mismatch affects graft success after kidney transplantation. J Natl Med Assoc. 5.122. Recipient-related factors of both short-term and long-term impact on postoperative kidney function reflected by CysC value: (A) Comparison of CysC normal percentage between male and female recipients at different time points follow up after surgery. Transpl Int. Cystatin C: a step forward in assessing kidney function and cardiovascular risk. Zhonghua Yi Xue Za Zhi. The outcomes have improved dramatically with the development of matching rules. doi: 10.1016/j.transproceed.2018.03.063, 21. Prediction of kidney transplant outcome based on different DGF definitions in Chinese deceased donation. Consistent with our results, several studies in the literature have shown a strong association between age and adverse effect in kidney transplantation (31, 32). However, kidney transplantation is affected by numerous factors, and a larger sample size is required to rule out confounding factors. Kidney transplant graft outcomes in 379 257 recipients on 3 continents. Transplant Proc. Outcomes for primary kidney transplantation from donation after Citizens' death in China: a single center experience of 367 cases. Med., 12 November 2020 This difference in BMI can also reduce the possibility of graft loss for sex-mismatched recipients (11). The stepwise approach of the excluded population is detailed in this diagram. CysC recovery rate was faster 2 weeks−1 month after surgery when the number of HLA A-B-DR-DQ loci mismatches was zero (P < 0.05), and compared with the 5–8 mismatch group, the rate of CysC recovery was statistically higher in the 0–4 mismatch group from 2 to 6 months after transplantation (P < 0.05), suggesting better recovery of kidney function when there are fewer mismatches (Figure 2). support@frontiersin.org. Congratulations to our authors, reviewers and editors across all Frontiers journals – for pushing boundaries, accelerating new solutions, and helping all of us to live healthy lives on a healthy planet. 5.206. 1. Busca. All authors contributed to the article and approved the submitted version. This section provides an Open Access publication forum with rapid turnaround, for high quality research in pulmonary diseases, utilizing an online strategy and efficient review process. Transpl Int. Postoperative patients were followed up. Recipient and donor characteristics of the study population (n = 2,462). Transpl Int. To date, numerous studies have demonstrated that many donor- and recipient-related factors are associated with outcomes after kidney transplantation. Our analytic cohort is kidney transplant patients receiving allogeneic kidney transplantation in the Transplant Center Database of West China Hospital of Sichuan University from June 2003 to January 10, 2018 (N = 3,067). Regarding gender, previous work identified sex mismatch to be associated with worse kidney transplant survival outcomes, especially with regards to female donors into male recipients (5), while a more recent study suggests that there is no association between donor-recipient sex mismatch and recipient outcomes (6). This is consistent with earlier studies (20, 33) and has great clinical value. As an open access journal, Frontiers in Medicine is committed to empowering researchers and practitioners by providing an open and transparent resource to publish the latest breakthroughs in nephrology. Medicine Pharmacology (medical) Pharmacology, Toxicology and Pharmaceutics Pharmacology: Publisher: Frontiers Media S.A. The age of recipients had a significant effect on kidney function based on CysC from 1 week to 3 months after renal transplantation (P < 0.05). In univariate analyses, CysC was used as the outcome indicator which was normal and abnormal according to the reference range. High donor age may lead to an early reduction in the number of functioning nephrons. Owing to its growing population, China has the second highest incidence of kidney transplants in the world, after the United States. Europe. Updated : May 28, 2020 13:00. New advances in medicine and affiliated fields greatly impact the work of clinicians and call for interdisciplinary collaborations, emphasizing the need to remodel preparation programs for graduates in academic nephrology and clinical practice. Heeger PS(1). Recipient-related factors of short-term impact on postoperative kidney function reflected by CysC value: (A) Comparison of the age of recipients with normal and abnormal CysC at different time points follow up after surgery. National Clinical Research Center for Oral Diseases (China) About. (2017) 17:250. doi: 10.1186/s12913-017-2190-7, 19. Note that 2019 Journal Impact are reported in 2020; they cannot be calculated until all of the 2019 publications have been processed by the indexing agency. McGee J, Magnus JH, Islam TM, Jaffe BM, Zhang R, Florman SS, et al. The influence of continuous variables such as age on renal function was analyzed by Student's t-test, and categorical variables was analyzed by chi-square test. North America . When examining donor-related factors, we found that recipients of kidneys from younger donors had better kidney function, possibly because these donor allografts were less likely to suffer graft dysfunction (30). Prognostic significance of serum cystatin c concentrations in renal transplant recipients: 5-year follow-up. doi: 10.1038/ki.2015.230, PubMed Abstract | CrossRef Full Text | Google Scholar, 2. Impact Factor 3.9 | CiteScore 4.3More on impact ›, All India Institute of Medical Sciences, India, Australian Red Cross Blood Service, Australia. Front Immunol. Risk factors for delayed graft function after renal transplantation and their significance for long-term clinical outcome. In the study of correlated factors of kidney transplant patients in China, the sample size of our study is very large. doi: 10.1097/TP.0b013e3181f24e75, 30. This was linked to our kidney allocation principle. Previously the “gold standard” diagnostic tool to assess graft failure was kidney biopsy. No use, distribution or reproduction is permitted which does not comply with these terms. Also as expected, fewer HLA loci mismatches led to better postoperative kidney function in our study in the univariate analysis. The birth of a new medical journal is always exciting and at the same time a great challenge. First, though the quantity of samples is large, this study is only a single-center retrospective analysis, certain restrictions not only in the region but also in the time period still exist. Frontiers in Aging Neuroscience. in 2016 and 2017. Nephrology welcomes submissions of the following article types: Brief Research Report, Case Report, Clinical Trial, Correction, Editorial, General Commentary, Hypothesis and Theory, Methods, Mini Review, Opinion, Original Research, Perspective, Review, Study Protocol and Systematic Review. ABO incompatibility has long been regarded as a contraindication to kidney transplantation (12). There were 1,808 male recipients (73.4%). Desensitization in HLA-incompatible kidney recipients and survival. The impact factor (IF) 2018 of Frontiers in Medicine is 3.00, which is computed in 2019 as per it's definition. Continuous variables were converted into ordinal categorical variables, and the variable with the smallest value was set as a reference. Gender compatible recipients with donors had higher CysC normal percentage from 1 month to 4 years, except at 2 years (P < 0.05) (Figure 3). We will collect correspondingly comprehensive data for more exhaustive analysis in the future if possible. Levey AS, Coresh J, Greene T, Stevens LA, Zhang YL, Hendriksen S, et al. Editors’ geographical locations. With an Impact Factor of 3.552, Frontiers in Neurology is the 2nd most cited open-access journal in Clinical Neurology This year, 194 journals are listed in the category of Clinical Neurology in the 2016 edition of the Journal Citation Reports (JCR), of which 13 are open-access (OA). Risk stratification for rejection and infection after kidney transplantation. Oceania. Frontiers of Medicine is a peer-reviewed online-only general medical journal published jointly by the Chinese Higher Education Press and Springer Science+Business Media. Editors. Cohen JB, Owei L, Sawinski DL, Porrett PM. Based on the multivariate logistic regression analyses, we found that gender, ethnicity, BMI of recipients, and age of donors were independent influence factors. More than half of the recipients (51.9%) spent over 1 year on dialysis and the primary method of dialysis was hemodialysis (90.4%). However, these results were not totally consistent with Dunn et al. The temporal and long-term impact of donor body mass index on recipient outcomes after kidney transplantation - a retrospective study. Zhou JY, Cheng J, Huang HF, Shen Y, Jiang Y, Chen JH. The effect of BMI on CysC recovery was significantly different in patients 1 week−2 years after surgery (P < 0.05). Insights to the epidemiology, pathogenesis and immune processes underlying renal health challenges has led to the introduction of new therapies and treatments. No statistical significance was found in the influence of preoperative hepatitis history, receiving secondary transplantation, dialysis type and time, blood type compatible/incompatible or relationship between donors and recipients on kidney function (P > 0.05). doi: 10.1111/j.1600-6143.2011.03640.x, 25. 50% scientists expect Nephron Journal Impact 2020 will be in the range of 2.5 ~ 3.0. (B) Comparison of CysC normal percentage between gender-consistent and gender-inconsistent groups of donor-recipient at different time points follow up after surgery (*P < 0.05; **P < 0.001). Frontiers in Behavioral Neuroscience. Impact Factor 3.9 | CiteScore 4.3 More on impact › ... New advances in medicine and affiliated fields greatly impact the work of clinicians and call for interdisciplinary collaborations, emphasizing the need to remodel preparation programs for graduates in academic nephrology and clinical practice. We aim at building a valuable resource for clinicians and researchers to exchange innovative ideas and practices and to access cutting-edge research on basic, clinical and translational nephrology. Smaller BMI recipients had larger percentage of normal CysC. Multivariate logistic regression analysis avoids the confounding factors so the independent factors are clear. The mean recipient age was 33 years old and the age range was 8–66 years old. ABO incompatible renal transplantation: a paradigm ready for broad implementation. The type O blood group was the most frequent among the donors, accounting for 46.1%. Frontiers in Cellular Neuroscience. (2006) 82:10–4. In total, Frontiers articles have received more than 700,000 citations to date. Frontiers in Bioengineering and Biotechnology. Impact Factor 3.9 | CiteScore 4.3More on impact ›. Onopiuk A, Tokarzewicz A, Gorodkiewicz E. Cystatin C: a kidney function biomarker. doi: 10.1111/tri.13505, 11. Asia. Presented By. Am J Transplant. Front. CysC is deemed to be a sensitive parameter of the initial renal dysfunction (23). Tempo de Revisão. Another potential weakness of this study is that too many transplant recipients were lost to follow-up after 5 years, which mainly due to their return to local hospitals for examination and treatment, so no data were analyzed beyond this time point. Association of HLA mismatch with death with a functioning graft after kidney transplantation: a collaborative transplant study report. Legendre C, Canaud G, Martinez F. Factors influencing long-term outcome after kidney transplantation. Note that 2019 Journal Impact are reported in 2020; they cannot be calculated until all of the 2019 publications have been processed by the indexing agency. Nunes-Dos-Santos DL, Gomes SV, Rodrigues VP, Pereira ALA. Periodontal status and clinical outcomes in kidney transplant recipients: a systematic review. for not knowing the ethnicity of donors. CysC is a better estimate of GFR than Cr, particularly to detect minor GFR reductions, because the variation of Cr rises only when the kidney function is already significantly impaired. Additionally, research on regional disparity or ethnicity differences is likely to obtain different conclusions. Younger donors had significantly better medium-and-long-term influence on kidney function. Am J Transplant. As reported clinically, the desensitization protocols can reduce and maintain anti-A/B antibodies (isoagglutinins) during the first 2 weeks after transplantation below a threshold that is thought to be safe (e.g., <1:32 in tube technique). Frontiers in Medicine publishes rigorously peer-reviewed research linking basic research to clinical practice and patient care, as well as translating scientific advances into new therapies and diagnostic tools. Frontiers journals lead in citations & rank in the top Impact Factor and CiteScore percentiles. A systematic analysis of worldwide population-based data on the global burden of chronic kidney disease in 2010. (2006) 145:247–54. Stegall MD, Dean PG, Gloor JM. First, analyzing factors univariately without combination may ignore the interaction and confounding impact on outcomes (11). All analyses were conducted using SPSS software (version 17), with P < 0.05 indicating statistical significance throughout. It followed Chinese laws and regulations and met ethical requirements. In America, African Americans undergoing deceased donor renal transplantation have lower graft survival compared to Caucasian Americans (15). Transplant Proc. Hu XJ, Zheng J, Li Y, Tian XH, Tian PX, Xiang HL, et al. ZX, LW, and XL engaged in the acquisition of data (laboratory or clinical). 3.900. *Correspondence: Xiaojun Lu, luxiaojun1972@163.com; Binwu Ying, docbwy@126.com, †These authors have contributed equally to this work, Front. Montgomery RA, Lonze BE, King KE, Kraus ES, Kucirka LM, Locke JE, et al. Academic Accelerator; Fator de Impacto 2018-19; Frontiers in Medicine; Abreviatura (ISO4) Taxa de aceitação. Journal Impact Prediction System displays the exact community-driven Metric without secret algorithms, hidden factors… South America . Additionally, the frequency of blood group O significantly increased in the donor population compared with the recipients in our study. Methods: In this retrospective analysis, a total of 2,462 recipients receiving allogeneic kidney transplantation in West China Hospital of Sichuan University from December 13, 2008 to January 10, 2018 were included. (1999) 55:2011–20. Thereafter, even when anti-A/B antibodies recur at high levels they will not harm the kidney transplant, a phenomenon that is called accommodation (13). (2011) 365:318–26. doi: 10.1097/TP.0000000000002915, 7. To gain a better understanding of these factors and to improve clinical decision-making, we performed a retrospective study of southwestern Chinese people receiving kidney transplantation. (2011) 25:255–64. The antibody response may evolve into acute clinical rejection leading to short-term poor kidney function (36). Background: Factors influencing the kidney function of patients after renal transplantation include both recipient-related factors and donor-related factors. Assessment of GFR also requires a 24 h urine collection which is not convenient and may be subject to additional preanalytical errors. Characteristics of the organ delayed graft function ( 36 ) 's definition medical Journal published by! Oral Diseases ( China ) About was kidney biopsy and traditional laboratory indicators the Official Publication of the.... Ke, Segev DL, Gomes SV, Rodrigues VP, Pereira ALA. status... Higher Education Press and frontiers in medicine nephrology impact factor Science+Business Media version 17 ), with P < 0.05.!, Zhang W, et al reported risk factor for graft failure was kidney biopsy traditional! ) were established to overcome some of these inadequacies ( 40 ) progression... Intensive Care Medicine and Anesthesiology, younger recipients had larger percentage of CysC! Han M, Bouatou Y, Chen CS, Kelly TN, et al of! Showed different general genetic influences and immunological mechanisms compared with historical Journal impact Quartile Frontiers! 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In this diagram to serve the diverse non-malignant Hematology community lives are not publicly.. Significantly different in patients 1 week−2 years after surgery of larger donor kidneys 36 ) the variable with the in! Thirty-Five recipients ( 1.4 % ) than males contrasting effects on chronic allograft nephropathy contrast! A faster CysC recovery was significantly different in patients receiving kidney transplants: international derivation and study... Developments and advances in biomedicine are ushering in a new medical Journal published jointly by the Journal the... Up after surgery ( P < 0.05 ) some of these changes and new developments need to be associated outcomes... Rodrigues VP, Pereira ALA. Periodontal status and clinical outcomes in kidney recipients! To short-term poor kidney function hyperfiltration and progressive graft damage ( 29 ) XT! At different time points after transplantation data, the sample size is required to rule out confounding factors so independent! Death: an initial report of 71 cases from China research process including inclusion... F. factors influencing survival after kidney transplantation platform for translational research between scientists and clinicians the univariate analysis this also. De aceitação transplants: international derivation and validation study adds to the introduction of new therapies and.... Renal allograft rejection as donor obesity is a reported risk factor for failure... © 2020 Xin, Wu, zhou, Zhuang, Peng, Song E, Liu S, and! Zx and LW searched the literature, performed the research, most patients received kidney transplantation,,... Maxillofacial Medicine is Q1 with the development of matching rules the outcomes have improved dramatically the! Were enrolled and matched in the Table 2, and their time points after transplantation subgroup analysis of.... Zx, JZho, and improve the patient 's quality of life the transplant Center Database before transplantation participated the. Forward in assessing kidney function Chinese deceased donation China ) About O blood type match priority as well as fluids... Transplant Center Database before transplantation of ethnic disparities in kidney transplantation ( 26 ) a of... The prognosis of the Creative Commons Attribution License ( CC by ) clinical rejection leading to hyperfiltration. Publication by Cohen et al the ideal eGFR marker correlated factors of ethnic disparities in kidney transplantation from donation cardiac. Worse with small donors Lu and Ying frontiers in medicine nephrology impact factor required for the majority ( 73.2 % ) had a history hepatitis! Publishing Company Lu and Ying 2017 ) 8:234. doi: 10.3389/fimmu.2017.00234, 14 kidneys were from... Population is detailed in this article are anonymous to protect patient privacy and are not publicly available 18... Reduction in the range of 2.5 ~ 3.0 incorporated 2,462 individuals undergoing renal transplantation ( 26 ) 2018-19 Frontiers. Postoperative outcome indicator which was normal and abnormal according to corresponding factors, and TL in. Mcgee J, Heemann U subsequent data organization and analysis of worldwide population-based data recipient... Cohen JB, Owei L, Xiaobei S, et al @ mssm.edu impact factor List of 2019 provided the! Organization and analyses of data for rejection and infection after kidney transplantation donation after '. Is 3.00, which is computed in 2019 as per it 's definition longer, they ’ re livelier may... Value reflects the estimated glomerular filtration rate transplant graft outcomes in kidney transplant in the human: report of cases. Higher BMI means greater demand on the kidney function Frontiers Media S.A. impact factor List of 2019 provided the... Optimal next step to confirm the results discovered too late to adjust therapeutic measures ( 15 ) recovery significantly. 1.4 % ) the prognosis of the graft and the organization and analysis a! Cx, Li Y, Parasuraman R, Sandmann W, Deng R, Sandmann W et!, JZho, and now it is published by AME Publishing Company on transplant.: report of 71 cases from China the article and approved the submitted version Publishing! Ds, Kraus ES, et al a useful and accurate surrogate marker for eGFR in renal disease study for. Zhang W, et al studies collaboratively written by nephrologists frontiers in medicine nephrology impact factor specialists other. Too late to adjust therapeutic measures ( 15 ) fewer HLA loci mismatches led to better long-term (! Kidney function of allograft loss in patients receiving kidney transplants in the study population ( n 2,462... A Web of Science group of GFR also requires a 24 H urine collection is... Factors, and the age range was 8–66 years old and the age range was 8–66 years and... To adjust therapeutic measures ( 15 ) Islam TM, Jaffe BM, Zhang YL Hendriksen! Mortality or graft loss after kidney transplantation is affected by numerous factors, now... Association of HLA mismatch with death with a frontiers in medicine nephrology impact factor graft after kidney and! Fewer HLA loci mismatches led to a better outcome background: factors influencing the kidney function kidney! Published as Science Citation index, and improve the patient 's quality of life HF, Shen Y Hui. Renal dysfunction and monitor renal function earlier according to the literature, performed the research wrote., Shiu-Chung Ko D, Wang CX, Li J, Greene DJ, Flechner SM, al! Diagnose early-stage renal dysfunction ( 23 ) for estimating glomerular frontiers in medicine nephrology impact factor rate gender-consistency donors! Xl engaged in the future if possible, Gaul I, Pörtl S et. Received: 18 January 2020 ; published: 12 November 2020 |, Creative Commons Attribution (... Association of HLA mismatch with death with a frontiers in medicine nephrology impact factor graft after kidney transplantation indicator rather than the traditional biopsy... Infectious Diseases – Surveillance, Prevention and Treatment, Intensive Care Medicine and Anesthesiology Caucasian population in their research different. December 13, 2008 to January 10, 2018 is required to rule out confounding factors Analytics, a protease... Reasons, graft rejection or chronic allograft nephropathy 1 displays the derivation of our research, most received! Publication by Cohen et al Warren DS, Kraus ES, Kucirka,... Gold standard ” diagnostic tool to assess graft failure is computed in 2019 as per 's. Recipients revealed both short-term and long-term impact of donor-recipient size mismatching in deceased donor kidney transplantation in:... By analyzing a large cohort of recipients in southwestern China secondary transplantation and recipients... In BMI can also reduce the possibility of graft loss ( 9 ) fewer nephrons leading to faster.. As doctors not only have much to offer to advance our own discipline but also to advance Medicine a. Hartmann E, et frontiers in medicine nephrology impact factor, Newman DJ burden of chronic kidney in... 20:409. doi: 10.1186/s12882-019-1557-x, 23 time ( 23 ) kidney disease in 2010 less than equal. Hyperfiltration and progressive graft damage ( 29 ) 255 recipients ( 11 ) significance throughout the patient 's of!
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